Glutathione-responsive paclitaxel dimer nanovesicles with high drug content.

نویسندگان

  • Qing Pei
  • Xiuli Hu
  • Junli Zhou
  • Shi Liu
  • Zhigang Xie
چکیده

Paclitaxel dimer-based nanovesicles, with an ultrahigh drug content, have been prepared through a nanoprecipitation method. The as-formed nanovesicles exhibit improved paclitaxel solubility, prominent colloid stability, GSH-triggered disassembly, effective cellular uptake and comparable cytotoxicity to Taxol.

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عنوان ژورنال:
  • Biomaterials science

دوره 5 8  شماره 

صفحات  -

تاریخ انتشار 2017